“I don’t want the Church if the Church doesn’t want me” - Mormonism’s impact on LGBTQ+ people: A case study of LGBTQ+ ExMormons

This study aims to find out ‘Mormonism’s impact on the lives of LGBTQ+ people’ and explore ‘the reasons why LGBTQ+ Mormons choose to leave the Church of Jesus Christ of Latter-day Saints (LDS Church).’ LDS Church has a long history of discrimination against its queer members and also notoriously campaigned to support Proposition 8 which was a California ballot proposition to define marriage between a man and a woman in 2008. The Church’s current rhetoric on LGBTQ+ people is “it is not a sin to have same-sex attraction but it is a sin to act on it.” The Church also announced its support for the Respect for Marriage Act at the end of 2022. While the previous studies usually include both queer Mormons and queer ExMormons, this study involves only ExMormons and takes its departure from a human rights perspective. Two important dimensions in the human rights field such as discrimination and freedom have been utilised to analyse the data and discuss the research questions. Semi-structured interviews with nine LGBTQ+ ExMormons from the USA were carried out. A qualitative content analysis has been adopted to analyse the data through theories of discrimination and freedom. The study focuses on results that impact the lives of LGBTQ+ Mormons such as reinforced gender roles, the Church’s lagging behind the US society, feelings of shame and denial of sexuality, celibacy and depression. Additionally, the levels of discrimination queer ExMormons have been exposed to and how they have chosen to leave the discriminatory environment have been discussed by operationalising discrimination and freedom

Effects of deleting mitochondrial antioxidant genes on life span

Reactive oxygen species (ROS) damage biomolecules, accelerate aging, and shorten life span, whereas antioxidant enzymes mitigate these effects. Because mitochondria are a primary site of ROS generation and also a primary target of ROS attack, they have become a major focus area of aging studies. Here, we employed yeast genetics to identify mitochondrial antioxidant genes that are important for replicative life span. In our studies, it was found that among the known mitochondrial antioxidant genes (TTR1, CCD1, SOD1, GLO4, TRR2, TRX3, CCS1, SOD2, GRX5, PRX1), deletion of only three genes, SOD1 (Cu, Zn superoxide dismutase), SOD2 (Manganese-containing superoxide dismutase), and CCS1 (Copper chaperone), shortened the life span enormously. The life span decreased 40% for Δsod1 mutant, 72% for Δsod2 mutant, and 50% for Δccs1 mutant. Deletion of the other genes had little or no effect on life span.Turkish State Planning Organisation Grant 2003K12069

Sequence variants of CYP345a1 and CYP6a14 gene regions in tribolium castaneum (Coleoptera: Tenebrionidae) adults treated with the novel characterized bolanthus turcicus (Caryophyllaceae) extract

In this study, various doses of plant extracts that obtained from Bolanthus turcicus was applied to an important storage pest Tribolium castaneum adults. Bolanthus turcicus is an endemic species and spreads on the Hasan Mountain above Karkin town (Turkey, Aksaray province). The plant species was collected from June to July with the field study to be carried out in this region. Obtained extract of plant was analyzed by gas chromatography mass spectrometry (GC-MS) method. The doses were defined during the study and the concentrations that kill 50% and 99% of the population were determined after applications. After 24 h, DNA was isolated from live and dead individuals that obtained from LC50 and LC99 concentration applications and analyzed for Cytochrome P450-mediated detoxification resistance genes, CYP345A1 and CYP6A14 gene regions, by polymerase chain reaction (PCR). CYP genes in insects are known to be rapidly regulated when exposed to insecticides. In the study, in order to screen for 206 bp and 353 bp fragments of CYP345A1 and CYP6A14 genes in T. castaneum adults were amplified using specific primers, respectively. DNA direct sequencing was performed on each template using the forward primer. When compared to the control, it is believed that mutation differences in live and dead individuals according to the sequencing results obtained from survival and dead adults, may allow these genes to play a protective role against the toxic effect of B. turcicus extract. © Shiraz University

Tourism Development Strategies in the Context of Coast, Culture and Agriculture-Büyükmenderes Basin

Turkey, during nearly in a hundred years of development period have lived a process where population and income in rural areas have decreased but on the contrary urban and coastal areas have developed. Now, one of every four people live in urban settlements. During this process, the living environment and the quality of life has negatively effected by the concentration of the urban areas not as the planning has foreseen, the concretion of urban surfaces and insufficient reinforcement area problems. The naturalness of the rural areas, product diversity, open space, the relations of production, rural culture and lifestyle has become longed qualifications. Büyükmenderes basin with its nature of accessibility, integrity of coastal-plain-mountain where combined, different geographies, naturalness, rich fauna and flora, the sea, lakes, rivers, hot springs, special products, historical values and cultural diversity has a special place. At the same time the country's most important coastal tourism are the focus of the surface of the rear axle Ku?adas?-Bodrum. Increase in the density of urban settlements, inadequate reinforcement measures and the loss of legibility, rural poverty and abandonment of settlements inhabited by the problems of this scope requires new improvements and the development of new principles of sustainability. In this context Büyükmenderes basin is in great potential. To participate in the production process, nature sports facilities, health tourism through thermal resources, cultural tourism, access to a rich diversity of fauna and flora, opportunities provided by sea, lake, river sources, the local culture, lifestyle, recognition of settling relations, accommodation with local properties for the region will take different roles at all levels and contains programmability. In this study, such urban settlements like Aydin, Soke specified in the above content, for Büyükmenderes basin development and promotion strategies will be examined for the integrity of coastal tourism, culture, agriculture and a proposal of a model will be developed.

Maya (Saccharomyces cerevisiae) sitoplazmik tiyoredoksinleri için ikinci bir elektron donörünün varlığını gösteren deliller

In yeast, the cytoplasmic thioredoxin system is composed of NADPH, thioredoxin reductase-1 (TRR1) and 2 thioredoxin genes (TRX1, TRX2). In this study, using yeast knockout mutants for TRR1, TRX1 and TRX2 genes, the role of the thioredoxin system in methionine sulfoxide reduction was investigated. Cells lacking both TRX1 and TRX2 genes simultaneously were not able to reduce methionine sulfoxides to methionine; however, mutants missing the TRR1 gene were able to reduce methionine sulfoxides to methionine, which showed that electrons could be transferred from NADPH to thioredoxins in the absence of TRR1. Similar results were observed for 3-phosphoadenosine 5-phosphosulfate reduction in the inorganic sulfate assimilation pathway. Results from both assays suggested that yeast cells have additional cytoplasmic thioredoxin reductase activity that could compensate for methionine sulfoxide reduction and sulfate assimilation in the absence of TRR1. This report also constitutes the first evidence that thioredoxins are the in vivo electron donors for methionine sulfoxide reductases in yeast

Maya (Saccharomyces cerevisiae) sitoplazmik tiyoredoksinleri için ikinci bir elektron donörünün varlığını gösteren deliller

In yeast, the cytoplasmic thioredoxin system is composed of NADPH, thioredoxin reductase-1 (TRR1) and 2 thioredoxin genes (TRX1, TRX2). In this study, using yeast knockout mutants for TRR1, TRX1 and TRX2 genes, the role of the thioredoxin system in methionine sulfoxide reduction was investigated. Cells lacking both TRX1 and TRX2 genes simultaneously were not able to reduce methionine sulfoxides to methionine; however, mutants missing the TRR1 gene were able to reduce methionine sulfoxides to methionine, which showed that electrons could be transferred from NADPH to thioredoxins in the absence of TRR1. Similar results were observed for 3-phosphoadenosine 5-phosphosulfate reduction in the inorganic sulfate assimilation pathway. Results from both assays suggested that yeast cells have additional cytoplasmic thioredoxin reductase activity that could compensate for methionine sulfoxide reduction and sulfate assimilation in the absence of TRR1. This report also constitutes the first evidence that thioredoxins are the in vivo electron donors for methionine sulfoxide reductases in yeast